Weidong Chen Peddi, A. Zheng, Y.F. Caffrey, M.
Dept. of Autom., Shanghai Jiao Tong Univ., China;
This paper appears in: Intelligent Control and Automation, 2004. WCICA 2004. Fifth World Congress on
Publication Date: 15-19 June 2004
Volume: 5, On page(s): 4650- 4655 Vol.5
ISSN:
ISBN: 0-7803-8273-0
INSPEC Accession Number: 8127509
Current Version Published: 2004-10-18
Abstract
To facilitate high-throughput macromolecular crystallography, there is a need to develop techniques and devices for automatic and rapid crystal handling. In this paper, we propose a novel manipulation protocol to realize an effective automated crystal harvesting and mounting system. We first discuss different vision-based object tracking and focus-based localization algorithms, which are essential in the crystal manipulation process. A capillary-loop coordinating mechanism is then presented for mounting the crystal for X-ray diffractometry. Experimental results using the proposed algorithms and mechanism are presented which are encouraging for the development of a fully automated crystal harvesting and mounting system.
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