Bio-X / News and Events
News -
Bio-X Graduate Student Fellowships 2009/2010
The Bio-X Leadership Council is pleased to announce the sixth annual
competition for Bio-X Graduate Student Fellowships. The fellowships
are the generous gift of an anonymous donor who is helping Stanford
strengthen graduate training in interdisciplinary biosciences and so
spur important new advances in science and engineering.
Seven 3-year Bio-X Graduate Student Fellowships and at least two
Bio-X SIGFs in Human Health will be awarded and will provide funding
for three years, to begin Fall Quarter 2009/2010. The funding is to
be utilized toward payments for graduate tuition and
stipend. Eligible graduate students must be 1) working in the lab of
a Bio-X affiliated faculty member, 2) starting their first, second,
or third year of a Ph.D. program on September 21, 2009. (Students
eligible for the Bio-X SIGF in Human Health may be starting their
fourth year of graduate studies on September 21, 2009) The Bio-X
Graduate Student Fellowship may not be combined with any other full
fellowship awards. Students who will be supported by other full
fellowship sources, such as NSF, NIH, SGF, during the 2009/2010
academic year are not eligible to apply.
Applications must be received, not postmarked by, March 20, 2009 at 5:00pm
For full details and the online application form, please visit:
http://biox.stanford.edu/grant/fs_grad_0910.html
Questions? Please send email to: bio-x_fellowship_applications at stanford.edu
Upcoming Workshop on Small-Angle X-ray Scattering and Diffraction
Studies in Structural Biology
A workshop on small-angle x-ray scattering and diffraction studies in
Structural Biology will be held April 9-12, 2009 at SSRL.
Online Registration is now available at: http://www
conf.slac.stanford.edu/smbsax/
The workshop consists of two days of lectures, and two days of
practical sessions on experimental and computational aspects of
small-angle x-ray scattering studies in biology, particularly
solution x-ray scattering. It will cover the following scientific and
technological topics:
-Review of non-crystalline diffraction studies in biology
-Information content of solution scattering
-Complementary use of crystallography and x-ray scattering
-Nucleic acid studies
-Protein folding
-Time-resolved studies
-Structural modeling approaches using solution scattering data
-Lipid membrane diffraction studies for membrane protein crystallization
-Diffraction studies on fiber and other non-crystalline biological systems
-Experimental facilities for structural biology on SSRL BL4-2
-Software developments at BL4-2
-ATSAS software tutorials
-Experimental tutorials on BL4-2
Lecturers include Dmitri Svergun (EMBL-Hamburg), Brian Shilton (Univ.
Western Ontario), Osman Bilsel (Univ. Massachusetts), Vadim Cherezov
(Scripps), Pehr Harbury (Stanford), Andrej Sali (UCSF), Daniel
Kirschner (Boston College) and SSRL SMB staff members. The workshop
dates immediately follow the West Coast Protein Crystallography
Workshop in Asilomar, CA.
Contact: H. Tsuruta, tsuruta at slac.stanford.edu
Stem cell policy may aid state research efforts
http://news.stanford.edu/news/2009/march11/med-stem%20cell-031109.html
$10 million gift for environmental program
Dan Emmett, '61, and his wife, Rae, have endowed the
Interdisciplinary Program in Environment and Resources with a $10
million gift through their Emmett Foundation.
http://news.stanford.edu/news/2009/march11/emmett-gift-environment-031109.html
Events -
March 11: Simbios Seminar
Speaker: Martin Stumpe, Stanford University
Title: De natura denaturantium - On the molecular basis of
urea-induced protein denaturation
Abstract: Protein unfolding by denaturants such as urea is a widely
used technique to study protein folding and stability. Despite the
widespread use of urea, however, the mechanism of urea-induced
protein denaturation is not yet fully understood on the molecular
level. In particular, it is controversially discussed whether
unfolding is driven by direct interactions of urea with the protein
or, alternatively, indirect interactions via urea-induced changes in
the water structure. Moreover, it is unclear whether polar or apolar
interactions are the main driving force for unfolding. To advance
understanding of the process at the molecular level, we have
performed comprehensive molecular dynamics of small peptides as well
as different proteins in aqueous urea solution. Our results suggest
that urea molecules interact preferentially with less polar parts of
the protein as well as the peptide backbone. As a result, water is
displaced from the solvation shell and the hydrophobic effect is
reduced. Further, the ability of urea to form hydrogen bonds helps to
avoid unsatisfied hydrogen bond sites at the backbone, but this is
only a secondary contribution. In summary, our results suggest a
mechanism which is a synthesis of seemingly opposing viewpoints.
Time/Location: 3:30pm (refreshments at 3:15pm), Clark Center, S360
Contact: Blanca Pineda <bpineda at stanford.edu>
______________________________________
March 12: Regenerative Medicine at Stanford (ReMs) Seminar
Speakers: Marc Levenston, Ph.D. (Mechanical Engineering) on
"Influence of scaffolds presenting biomimetic ligands on in vitro
chondrogenesis" and Ching-Pin Chang, M.D./Ph.D. (Cardiovascular
Medicine, Bio-X) on "Chromatin regulation of cardiac growth,
differentiation and morphogenesis"
Clark S360 at 12:00 pm
The goal of REMS is to create a forum for Stanford researchers to
meet, hear about what is going on in stem cell biology and
regenerative medicine at Stanford, and spark collaborations. The
topics include all areas of regenerative medicine, broadly defined,
ranging from fundamental biological principles and basic science
advances to novel applications in biotechnology, stem cell biology,
and human disease.
Contact: reh at stanford.edu
______________________________________
March 12: Bio-X Seminar
Bio-X Frontiers in Interdisciplinary Biosciences seminar
Speaker: Judith Frydman, Associate Professor of Biology at Stanford University
Seminar Title: Molecular Origami: the complex art of protein folding
in the cell
Time/Location: 4:15pm, Clark Center Auditorium
Web: http://biox.stanford.edu/courses/459seminar_mar12.html
Contact: fsincock at stanford.edu
______________________________________
March 16: Stem Cell Research Seminar Series
Joe Costello, Ph.D., Assistant Professor of Neurological Surgery, UCSF
Genetic and Epigentic Alterations in Sporadic Cancers
Noon - 1:00pm at 1050 Arastradero Rd.
Contact: Eric Chiao <etc at mac.com>
______________________________________
March 18: IEEE Meeting Announcement
The Institute of Electrical and Electronic Engineers (IEEE)
Engineering in Medicine and Biology Society (EMBS)
Santa Clara Valley Chapter
http://ieee.org/scv/embs
Meeting Announcement
Wednesday, March 18, 2009, 7:30 pm, Clark Center auditorium, Stanford
University
Optional Dinner, NEW LOCATION: Nexus Cafeteria in the Clark Center,
6:15 pm (no host, no reservations)
A Novel Technology to Improve the Effectiveness of Colonoscopy
Lex Bayer, VP of Product Development, Avantis Medical Systems
Abstract: Colorectal cancer is the second leading cause of cancer
death in the United States. Adults 50 years of age and older are
advised to routinely undergo colorectal cancer screening as a
preventative measure. Much literature has been published
demonstrating that the traditional colonoscopy procedure misses a
significant percentage of lesions and cancers. The Avantis Medical
Systems 3rd eye Retroscope was developed as an adjunct product
designed to improve the diagnostic yield of colonoscopy
procedures. The device is a miniature disposable imaging device that
illuminates and delivers a continuous retrograde view of the colon.
It allows the physician to look behind the folds and flexures in the
colon to find lesions that might otherwise be hidden. A second video
processor ties in with the main colonoscope camera system to provide
a split screen showing a simultaneous forward and rear views to
create a 360 degree view of the colon. The device employs novel
techniques in the field of image sensors, optics, image processing,
and catheter design. Research and development of the Third Eye
Retroscope and published clinical results will be presented. In
addition, an overview of recent technological advancements in the
field of colonoscopy will be discussed.
______________________________________
April 6: Stem Cell Research Seminar Series
Julien Sage, Ph.D., Assistant Professor, Stanford University
The Retinoblastoma (RB) Tumor Supressor Gene Family in Stem Cells and Cancer
Noon - 1:00pm at 1050 Arastradero Rd.
Contact: Eric Chiao <etc at mac.com>
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