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Taibi BEN-HADDA


Université Mohamed 1ER
Faculté des Sciences
Av. Mohamed VI
60000 OUJDA
Morocco
email: benhadda@sciences.univ-oujda.ac.ma
Phone: +061-75-31-35
Web site


Fields of Interest: Design of organometallics and therapeutic agents





Curriculum Vitae


Pr Taibi BEN-HADDA

Organométalliques et Catalyse

Né en 1959 à Beni-Amir Est à Beni-Mellal (Maroc)
Ph.D en 1987 à l'Université de Rennes 1 (France), sous la direction de Dr. H. Le Bozec Et Prof. P.H. Dixneuf.

Objectifs visés:
Notre recherche a pour intérêt la modification des propriétés des complexes organométalliques et la synthèse des hétérocycles soit pour la catalyse, ou pour la pharmacie.

Collaborateurs et leurs Etablissements:

1- Professeur Pierre H. Dixneuf: Catalytic Engineering - Catalysis & fine Chemistry.
http://www.umr6509.univ-rennes1.fr/site_anglais/individual_pages/dixneuf/
http://www.sfc.fr/Prix/Astruc_Dixneuf.htm

2- Professeur Ann T. Kotchevar: Department of Chemistry
California State University, Hayward
25800 Carlos Bee Blvd.Hayward, CA 94542-3087 USA. Spécialité : Application des complexes de Vanadium.
http://www.sci.csuhayward.edu/cgi-bin/chemistry.cgi

3- Professeur Michael Waring: Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK. Spécialité : Etude des interactions médicament/ ADN.

4- Professeurs Abdelali Kerbal et Najib Ben Larbi: Department of Chemistry, Sciences Faculty of D'Har Elmehraz, , Fès 30000, Morocco. Spécialité : Synthèse Organique.

5- Professeur J-P. Launay : Centre d'Elaboration de Matériaux
et d'Etudes StructuralesToulouse, France. http://www.cemes.fr/r2_rech/r2_sr2_gns/th1_2_2_etransf.htm


Mes Sites de recherche biblio préférés:

* http://highwire.stanford.edu/
* http://www.pharmacorama.com/
* http://journals.iucr.org/
* http://www.gfmer.ch/Medical_journals/
* http://www2.chemie.uni-erlangen.de/
* http://www.organic-chemistry.org/Prog/peo/index.html
* http://www.scirus.com/srsapp/


Liste des Brevets:

1- Bennani, B., A. Kerbal, N. Ben Larbi, T. Ben-Hadda. Synthesis and application of iso-thio-chromeno[3,4-e][1,2]oxazine (TCO) as new anti-tumoral agents. Moroccan Patent No. 2771, 2004.

2- Bennani, B., A. Kerbal, N. Ben Larbi, T. Ben-Hadda. Synthesis and application of some sprio-isoxazolines as new anti-HIV agents. Moroccan Patent No. 2770, 2004.

3- Bennani, B., A. Kerbal, N. Ben Larbi, T. Ben-Hadda. Synthesis and application of spiro-isoxazolines as new anti-tubercular agents. Moroccan Patent No. 2769, 2004.

http://www.taacf.org/publications.htm

Liste des publications significatives:

Armed Imidazo [1,2-a ] Pyrimidines ((Pyridines):Evaluation of Antibacterial Activity
A.Anaflous, N. Benchat, M. Mimouni, S. Abouricha, T. Ben-Hadda, B. El-Bali, A. Hakkou and B. Hacht
Letters in Drug Design &Discovery, 2004, 1, 224-229.

3-Nitroso-2-phenylimidazo[1,2-a]pyrimidine
Abderahmane Anaflous, Nour-Eddine Benchat, Taibi Ben-Hadda, Brahim El Bali and Michael Bolte, Acta Cryst. (2004). E60, o1131±o1132.
3-(Anthracen-9-ylmethylene)-2,4-dimethyl-3H-benzo[1,5]diazepine.
A. Megzari, B. El Bali, T. Janati, A. Kerbal, N. Benlarbi, T. Benhadda, M. Mimouni and M. Bolte, Acta Cryst. (2003). E59, o606-o607.

6-Phenyl-4,5-dihydropyridazin-3(2H)-one
S. Abourichaa, N. Benchat, A. Anaflous, A. Melhaoui, T. Ben-Hadda, B. Oussaid, B. El Bali and M. Bolte, Acta Cryst. (2003). E59, o802-o803.
5-(2-Chlorobenzyl)-2-(2-hydroxyethyl)-6-methylpyridazin-3(2H)-one
S. Abourichaa, N. Benchat, A. Anaflous, A. Melhaoui, T. Ben-Hadda, B. Oussaid, M. Mimouni, B. El Bali and M. Bolte, Acta Cryst. (2003). E59, o1041-o1042.

Impact of Dimroth Rearrangement on anti-Tuberculosis Activity of 3-armed-Imidazo[1.2-a]Pyrimidines IMP (-Pyridines) IP
T. Ben-Hadda, N. Benchat, B. El-Bali, S. Abouricha, M. Moueqqit and M. Mimouni, Medicinal and pharmaceutical Chemistry, 2003, 0301001, 1-18.

Chiral Methyl-7,8,9-trichloro-6,7,8,9-tetrahydro-5-oxopyrido- [2,3-a]indolizine-10-carboxylates (OPIC)
N. Ben Larbi, M. Daoudi, N. Sam, M. Mimouni, S. Elkadiri and T. Ben-Hadda, Molecules, 2002, 7, M277.

Novel trichloroindolizine derivatives via intramolecular acylation of a bis-(chloroacyl)-bipyridine
Najat Sam , Sghir Elkadiri , Hubert Le Bozec , Loic Toupet , Maria Daoudi , Najib Bitit , Taibi Ben Hadda and Pierre H. Dixneuf. J. Chem. Soc., Perkin Trans. 1, 2002, (14), 1688 - 1692.

Novel Cytotoxic OxopyridoIndolizines: iso-Propyl-7,8,9-tri-Chloro-6,7,8,9-tetra-Hydro-5- Oxo- Pyrido [2,3-a] Indolizine-10-carboxylates.
Franco Zunino, Ann T. Kotchevar, Michael Waring, Maria Daoudi, Najib Ben Larbi, Mostafa Mimouni, Najat Sam and Taibi Ben-Hadda, Molecules, 2002, 7, 628-640.

2,3-Bifunctionalized Quinoxalines: Synthesis, DNA Interactions and Evaluation of Anticancer, Antituberculosis and Antifungal Activity.
A. Hakkou, M. Bouakka, R. Touzani, S. Elkadiri, A. Ramdani, A. Kotchevar, T. Ellis, M. Waring, T. Ben-Hadda. Molecules, 2002, 7, 641-656.

Efficient Synthesis Of New nitrogen Donor Containing Tripods Under Microwave Irradiation and Without Solvent
Rachid Touzani, Abdelkrim Ramdani, Taibi Ben-Hadda, Sghir El Kadiri, Olivier Maury, Hubert Le Bozec and Pierre H. Dixneuf., Synthetic Comm., 2001, 31(9), 39-45.

Carbonyl and Chloro Complexes of Ruthenium(II) Containing 3,3'-diester-2,2'-Bipyridyl Ligands
Taibi Ben-Hadda, Najat Sam, Hubert Le Bozec and Pierre Dixneuf. Inorg. Chem. Commun., 1999, Vol 2/10, pp. 460-462.





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