Latest Headlines
Scripps Scientists Uncover Mimicry at the Molecular Level that Protects Genome Integrity
Study draws new parallels between the Rad60 DNA repair factor and SUMO; both essential for maintaining genome stability during replication.
Zenobia Successfully Completes Initial Phase of its Service Agreement with Syntonix
Zenobia completes three unique protein structures during the first five months of the agreement.
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Scientists Find Structure of a Protein that Makes Cancer Cells Resistant to Chemotherapy
A research team at the Scripps Research Institute has obtained the first glimpse of a protein that keeps certain substances, including many drugs, out of cells.
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Wyatt Technology Unveils New Brochure for its Newly Launched DynaPro NanoStar Protein Analysis Tool
Wyatt Technology Corporation has published a new brochure to support the launch of its new Dynamic Light Scattering (DLS) instrument, the DynaPro NanoStar.
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Scientists Create First Crystal Structure of an Intermediate Particle in Virus Assembly
A research team at the Scripps Research Institute has been able to produce the first crystal structure of a virus particle caught in the midst of assembling its impenetrable outer protein coat.
Recent Posters
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MED-SuMo and MED-Hybridise: exploit all PDB macromolecule structures to design/optimize innovative leads
MEDIT
Obtaining structural information on fragment-protein target is a key factor and also a major limitation. We’ve used MED-SuMo and MED-Hybridise to query and mine the PDB seeking for similar interaction surfaces. MED-portions were used to design novel scaffolds (GPCR) and decorate a given scaffold (kinase). We have analysed the scaffolds in regard to their diversity, their presence in PubChem, PDB and other libraries.
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Phase Diagram Visualization via Continuously-Fed Crystallization: Experiments and Model
University of Minnesota
A continuously-fed crystallization chamber is manufactured to allow phase diagram visualization. This microfluidic system allows the experimenter to screen a large range of salt and protein concentrations in one experiment. This allows the experimenter to predict the protein phase diagram in a single experiment. A continuous-feed crystallization chamber has been successfully fabricated and characterized in terms of its flow profile, and has successfully predicted the phase diagram for lysozyme.
Current Vacancies
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Postdoctoral Scientist in Single Cell Expression Profiling
TATAA Biocenter AB
Gothenburg, Sweden
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Postdoctoral Scientist in Proteomics of Ageing
Center for Advanced Research in Biotechnology
Rockville, USA
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Metabolomics Scientist in Nutrition
Nestlé Research Center
Lausanne, Switzerland
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Laboratory Technician
Nestlé Research Center (NRC)
Lausanne, Switzerland
Upcoming Events
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DxRx Summit: Nucleic Acid Diagnostics & Therapeutics Summit, Boston, MA, USA
12 May 2009 - 13 May 2009
The inaugural DxRx Summit will be a meeting focusing on the future in nucleotide drug therapy and diagnostic tools. Presentations include talks from the leaders in pharmaceutical companies discussing the state of their latest in RNAi drug research and the current state of some of their products currently being trialled.
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Advances in Microarray Technology, Stockholm, Sweden
19 May 2009 - 20 May 2009
The 5th Annual Advances in Microarray Technology (AMT) conference covers the latest developments and applications in the rapidly expanding field of microarrays.
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Power Scientific Unveils Incubator Models more>>>
Webcasts
Crystallographic Investigations on Insulin: Discovery and Development Applications
Gerd Schluckebier, Principal Scientist, Novo Nordisk A/S, speaking at Advances in Protein Crysyallography 2008
Identification of Macromolecular Assemblies in Crystalline State
Eugene Krissinel, Researcher, European Bioinformatics Institute, speaking at Protein Crystallography 2008
Automation, Robotics and Remote Access at the SSRL Protein Crystallography Beam Lines
Clyde Smith, Staff Scientist, Stamford University, speaking at Advances in Protein Crystallography 2008
Market Reports
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Multiplexed Diagnostics 2008 Market Report
Published May 2008
Multiplexed diagnostics are the wild west of medicine. Technology is established, regulation is limited and the number of new biomarkers exploding. First-movers are grabbing biomarker territories, combining independent measurements for efficiency and mining molecules for multivariate panels. All the while demand is high for improving diagnoses and predicting responses to treatment. The challenges, however, are uncertain reimbursement, unclear business models and ever-intensifying competition. On
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