School of Crystallography, Birkbeck
School of Crystallography, Birkbeck

Publications 2009
Bodey AJ, Kikkawa M, Moores CA.9-Angström structure of a microtubule-bound mitotic motor (2009). J Mol Biol. May 1;388(2):218-24. Epub 2009 Mar 10. PMID: 19285086 [PubMed - in process]

Carlomagno F, Guida T, Anaganti S, Provitera L, Kjaer S, McDonald NQ, Ryan AJ, Santoro M (2009). Identification of tyrosine 806 as a molecular determinant of RET kinase sensitivity to ZD6474. Endocr Relat Cancer. Mar;16(1):233-41. Epub 2008 Nov 24. PMID: 19029224 [PubMed - in process]

Charalambous K, O'Reilly AO, Bullough PA, Wallace BA. Thermal and chemical unfolding and refolding of a eukaryotic sodium channel. Biochim Biophys Acta. 2009 Feb 20. [Epub ahead of print] PMID: 19232514 [PubMed - as supplied by publisher]

Clare DK, Bakkes PJ, van Heerikhuizen H, van der Vies SM, Saibil HR (2009). Chaperonin complex with a newly folded protein encapsulated in the folding chamber. Nature. Jan 1;457(7225):107-10. PMID: 19122642 [PubMed - indexed for MEDLINE]

Drechsler A, Miles AJ, Norton RS, Wallace BA, Separovic F (2009). Effect of lipid on the conformation of the N-terminal region of equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study. Eur Biophys J. Apr 3. [Epub ahead of print]

Fronzes R, Schäfer E, Wang L, Saibil HR, Orlova EV, Waksman G (2009). Structure of a type IV secretion system core complex. Science. Jan 9;323(5911):266-8. PMID: 19131631 [PubMed - indexed for MEDLINE]

Gooptu B, Lomas DA (2009). Conformational Pathology of the Serpins: Themes, Variations, and Therapeutic Strategies. Annu Rev Biochem. Feb 26. [Epub ahead of print] PMID: 19245336 [PubMed - as supplied by publisher]

Gooptu B, Miranda E, Nobeli I, Mallya M, Purkiss A, Brown SC, Summers C, Phillips RL, Lomas DA, Barrett TE (2009). Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J Mol Biol. Apr 10;387(4):857-68. Epub 2009 Feb 14. PMID: 19232354 [PubMed - indexed for MEDLINE]

Halling-Brown, M., Moss, D., Sansom, C., Shepherd, A. (2009). A Computational Grid Framework for Immunological Applications. Accepted for publication in Philosophical Transactions of the Royal Society A

Hsu ST, Cabrita LD, Fucini P, Dobson CM, Christodoulou J. Structure, Dynamics and Folding of an Immunoglobulin Domain of the Gelation Factor (ABP-120) from Dictyostelium discoideum. J Mol Biol. 2009 Mar 10. [Epub ahead of print] PMID: 19281823 [PubMed - as supplied by publisher]

Jakubowski SJ, Kerr JE, Garza I, Krishnamoorthy V, Bayliss R, Waksman G, Christie PJ (2009). Agrobacterium VirB10 domain requirements for type IV secretion and T pilus biogenesis. Mol Microbiol. Feb;71(3):779-94. Epub 2008 Dec 1. PMID: 19054325 [PubMed - indexed for MEDLINE]

Lasker K, Topf M, Sali, A, Wolfson H. (2009) Inferential optimization for simultaneous fitting of multiple components into a cryoEM map of their assembly. J Mol Biol, in press.

Meng G, Fronzes R, Chandran V, Remaut H, Waksman G (2009) . Protein oligomerization in the bacterial outer membrane (Review). Mol Membr Biol. 2009 Apr;26(3):136-45. Epub 2009 Feb 14. PMID: 19225986 [PubMed - in process]

Mulder AM, Glavis-Bloom A, Moores CA, Wagenbach M, Carragher B, Wordeman L, Milligan RA (2009). A new model for binding of kinesin 13 to curved microtubule protofilaments. J Cell Biol. Apr 6;185(1):51-7. Epub 2009 Mar 30. PMID: 19332892 [PubMed - in process]

Nobeli I, Favia AD, Thornton JM (2009). Protein promiscuity and its implications for biotechnology. Nat Biotechnol. Feb;27(2):157-67. PMID: 19204698 [PubMed - in process]

Okorokov AL, Orlova EV (2009). Structural biology of the p53 tumour suppressor. Curr Opin Struct Biol. 2009 Mar 13. [Epub ahead of print] PMID: 19286366 [PubMed - as supplied by publisher]

Pappalardo, F., Halling-Brown, M.D., Rapin, N., Zhang, P., Alemani, D., Emerson, A., Paci, P., Duroux, P., Pennisi, M., Palladini, A., Miotto, O., Churchill, D., Rossi, E., Shepherd, A.J., Moss, D.S., Castiglione, F., Bernaschi, M., Lefranc, M.P., Brunak, S., Motta, S., Lollini, P.L., Basford, K.E., Brusic, V. (2009). ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design, and optimization. Briefings in Bioinformatics. In Press.

dos Reis M, Wernisch L (2009). Estimating translational selection in eukaryotic genomes. Mol Biol Evol. Feb;26(2):451-61. Epub 2008 Nov 25. PMID: 19033257 [PubMed - indexed for MEDLINE]

Roffey J, Rosse C, Linch M, Hibbert A, McDonald NQ, Parker PJ (2009). Protein kinase C intervention: the state of play. Curr Opin Cell Biol. 2009 Apr;21(2):268-79. Epub Feb 23. PMID: 19233632 [PubMed - in process]

Vaughan CK, Piper PW, Pearl LH, Prodromou C (2009). A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s. FEBS J. 2009 Jan;276(1):199-209. Epub 2008 Nov 20. PMID: 19032597 [PubMed - indexed for MEDLINE]

Wendler P, Shorter J, Snead D, Plisson C, Clare DK, Lindquist S, Saibil HR (2009) . Motor mechanism for protein threading through Hsp104. Mol Cell. 2009 Apr 10;34(1):81-92. PMID: 19362537 [PubMed - in process]

White HE, Hodgkinson JL, Jahn TR, Cohen-Krausz S, Gosal WS, Müller S, Orlova EV, Radford SE, Saibil HR (2009). Globular Tetramers of beta(2)-Microglobulin Assemble into Elaborate Amyloid Fibrils. J Mol Biol. 2009 Apr 5. [Epub ahead of print] PMID: 19345691 [PubMed - as supplied by publisher]

Zhou JJ, Robertson G, He X, Dufour S, Hooper AM, Pickett JA, Keep NH, Field LM (2009). Characterisation of Bombyx mori Odorant-Binding Proteins Reveals that a 'General Odorant-Binding Protein' Discriminates Between Sex Pheromone Components. J Mol Biol. 2009 Apr 13. [Epub ahead of print] PMID: 19371749 [PubMed - as supplied by publisher]

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